DUBLIN O MEDICAL PRESS. “s ALUs PopULI supreM.A. LEX." No. ccoxcI. vol. XVI. DUBLIN : WEDNESDAY, JULY 1, 1846. price sixPENCE, st AMPED, oRIGINAL communications. On Syphilitic Inflammation of the Eye (continued.) By A. Jacob, M.D., F.R.C.S.I., Professor of Ana tomy and Physiology in the Royal College of Sur geons, and one of the Surgeons of the City of Dublin Hospital............................... - MEETINGS OF SOCIETIES. Roy AL MEDICAL AND CHIRURGICAL SocIEty.— Cases of Melanosis, with Observations. By Holmes Coote, F.R.C.S., Surgeon to the North London Ophthalmic Institution..................................... Case of Rupture of the Heart from fatty degenera tion of that Organ. By R. H. Meade, F.R.C.S. - ry ........ *-........ of Bradford........... Hydatid Cyst, either originating in or pressing upon the Prostate Gland. By G. Lowdell, late House Surgeon to the Sussex County Hospital............... REviews AND NoTICEs of Books. A Manual of Operative Surgery based on Normal and Pathological Anatomy. By J. F. Malgaigne. Trans lated from the French by Frederick Brittan, A.B.... 6 Mr. Trant's Hernia Bistoury—Letter from Messrs. Read & Co........................................................ 7 PRoceedings of THE PHARMACEUTICAL Society.— Fifth Anniversary Meeting.—Draft of an Act of Parliament.................................................... 8 Discussion relative to Life Members’ Subscriptions. 10 LEADING ARTICLES. MEsMER Us TRIUMPHANs........................................ 11 PREs ENTATION of AN ADDREss to R. CARMICHAEL, METEOROLOGICAL, TABLES. Royal College of Surgeons, Dublin........................... 16 Portarlington, Queen's County.......... - 16 Royal Observatory, Greenwich............................... I6 ORIGINAL COMMUNICATIONs. ON SYPHILITIC INFLAMMATION OF THE EYE. (Continued.) By A. JAcob, M.D., F.R.C.S.I., Professor of Anatomy and Physiology in the Royal College of Surgeons, and one of the Surgeons of the City of Dublin Hospital. The depositions of lymph and other changes in the organi zation and appearance of the iris are thus noticed by Mr. Lawrence—“The change of colour which the organ undergoes is one of the most striking characters of iritis. A light coloured iris assumes, under inflammation, a yellowish or greenish tint; occasionally, it is distinctly yellow ; and, if the eye be blue, a bright green is some times seen. Generally, however, the tint, whether yellow or green, is of a dull and muddy cast, and darker than in the sound state. In ease of the iris being naturally dark coloured, it presents, when inflamed, a reddish tinge. Together with these changes of colour, there is a complete loss of its natural brilliancy; it becomes dull and dark, and the beautiful fibrous arrangement, which characterizes it in the healthy state, is either confused or entirely lost. These changes which are rendered particularly obvious by the contrast between the inflamed and the sound eye, commence in the pupillary margin. In an early period, the very edge of the pupil alone may be affected; the internal circle then becomes altered in colour, and thick ened; and afterwards the change spreads gradually to the external or ciliary edge of the iris. This alteration of colour is produced by effusion into the texture of the organ; and the particular tint is such as would arise from blending with the natural colour of the iris that of the lymph, which is yellowish or brownish. The deposition ºf lymph takes place under various modifications in syphi litic iritis; 1st, its effusion into the texture of the iris generally causes the changes of colour just described. 2ndly, it may be deposited in a thin layer, covering a larger or smaller surface. In this way, the edge of the Pupil first, and subsequently the lesser circle of the iris **sume a reddish brown or rusty colour in the beginning Wor... XVI, of the affection. The discoloured part has a rough villous appearance, when closely inspected, and we shall generally find, on careful examination, more particularly on looking at the part sideways, that slight elevation and irregularity of surface are produced by this new deposit. Sometimes the stratum of lymph has a light yellowish brown or ochrey tint, and a loose villous texture, rising into ob viously prominent masses. The rusty colour is the most common, and is observed particularly in blue irides; the other is seen in the gray, or the mixture of gray and orange. This kind of deposit is generally confined to the inner circle of the iris; but the outer circle is usually, at the same time, more or less discoloured and dull. 3rdly, the lymph may be effused in distinct masses—that is, in small drops or tubercles of a yellowish or reddish brown colour; sometimes they are of a bright red, and sometimes yellowish. They vary in size from that of a pin's head to a split pea. Often there is only one; there may be two, three, or more. They may be deposited on the edge of the pupil, or in any part of the anterior surface of the iris. When the inflammation is very active, and has been neglected or improperly treated, the lymph is sometimes secreted so abundantly as nearly to fill the anterior chamber; in which case it has a light dirty yellowish tint, and often a looseness of texture, with semi-transpa rency. 4thly, under violent inflammatory action blood itself is sometimes effused, and is mixed, in a coagulated state, with the tubercular masses of lymph. I have seen such effusion of blood where the inflammation has not been of the most violent kind. 5thly, lymph may be poured out from the margin of the pupil or the uvea, so as to agglutinate them partially or generally to the capsule of the crystalline. A mass of lymph sometimes fills the pupil. More commonly, a thin grayish web or film stretches across the opening, which loses its clear black colour, and has a cloudy appearance. Lymph may be effused in considerable quantity into the posterior chamber, and either make its way through the pupil into the anterior chamber, cause a bulging of the sclerotica, or penetrate that membrane, and form a tumour under the conjunctiva." A